1) “B Positive,” 9:30 p.m., CBS. Already a good show, this has had a drastic makeover for its second season. At the core is Gina, a good-hearted (if sometimes daft) soul, brilliantly played by Annaleigh Ashford. She inherited a fortune … and bought the retirement home where she works. That lets the show add a flock of newcomers. It already had two Tony-winners, Ashford and Linda Lavin (they’re shown here); now it adds two more, Ben Vereen and Priscilla Lopez, plus Jane Seymour and Hector Elizondo.
2) “Walker” season-opener, 8 p.m., CW. The second season of this “Walker, Texas Ranger” spin-off starts with our hero in peril. He finally learns why Micki, his partner in the Rangers, is working undercover. Also, his mother frets, now that the Davidsons (foes of the Walkers) have returned.
3) “Star Trek: Prodigy” debut, any time, Paramount+. Here’s a new twist for the “Trek” empire: It’s a computer-animated show aimed at kids – it will eventually air on Nickelodeon – but likely ro please grown-ups. An abandoned Starfleet vehicle is discovered by six outcasts – three teens, an 8-year-old, an impenetrable blob and a non-corporal lifeform. They fly it, with the help of a training video of Captain Janeway (Kate Mulgrew); John Noble voices the evil Diviner, with Jimmi Simpson as his robot.
4) “What We Do In the Shadows” season-finale, 10 p.m., FX, rerunning at 10:40 and 11:20. Last week brought the death of Colin, the “energy vampire.” (Such folks, it turns out, automatically die on their 100th birthday.) As this terrific show wraps its season, people mourn someone they usually mocked.
5) ALSO: On its only night without the World Series, Fox eagerly returns to football. At 8:20 p.m., it has the Arizona Cardinals (the NFL’s only undefeated team) hosting the Green Bay Packers (one of only two with a 6-1 record). Also, BBC America is starting a 102-hour “Doctor Who” marathon. It will peak with the TV debut of the animated “Evil of the Daleks” (8-11:30 p.m. Saturday) and then the new season-opener, at 2:25 and 8 p.m. Sunday.